Phosprenyl usage as part of the complex therapy of feline chronic coronavirus infection complicated by toxoplasmosis

Feline enteric coronavirus (FECV) infects enterocytes and causes inflammation of the intestinal mucosa in young cats, resulting diarrhea. In adult cats infection is usually asymptomatic, but constant circulation FECV feline population increases likelihood mutation, as a result which about 5-10% infected develop virulent strain virus that lethal infectious peritonitis – FIP. The purpose this study was to effectiveness Phosprenyl (PP), an immunomodulator with antiviral activity (active substance - polyprenyl phosphate), treatment chronic partially complicated by toxoplasmosis.
 A total 117 were under observation, 10 also had toxoplasmosis. diagnosis confirmed determination antibodies methods IHA ELISA, well ultrasound examination abdominal organs. Prescribed treatment: per os, 1 ml , twice day, course 2-4 months; Gamavit daily, s/c, days, repeated after 3 weeks; 3-4 times. As symptomatic therapy, drugs used primarily improve condition stool, toxoplasmosis Fansidar. At end symptoms gastrointestinal tract damage disappeared all patients. If before start majority patients demonstrated changes characteristic anemia (a significant decrease number red blood cells hemoglobin levels), then months, indices erythropoiesis completely normalized. toxoplasmosis, detected CBC test, increase neutrophils. biochemical profile these patients: increased enzymes aspartate aminotransferase (AST) alanine (ALT) found hyperbilirubinemia, indicates greater liver its detoxification function during disease caused simultaneously toxoplasmas. returned normal. 
 Thus, use for months reduces duration (including cases toxoplasmosis), prevents exacerbation possible fatal outcome. Long-term PP form recommended.